COVID-19 RNA Testing Technology Assessment


With the ongoing COVID-19 pandemic, and in response to high demand, a multitude of diagnostic tests for the detection and monitoring of the spread of the SARS-CoV-2 virus have been developed. This living document aims to survey the technical aspects of these diagnostic tests, outline the features and current limitations of their underlying technologies, formulate a modular framework for the assessment of the existing (and upcoming) tests workflows, and help depict a clearer and more comprehensive picture of this rapidly evolving space. With this manuscript as a starting point, we aim to help orchestrate a community effort to identify potential pitfalls and bottlenecks in the existing testing workflows—with the ultimate goal of paving the way to more sensitive, robust, scalable, and widespread tests for maximal social impact.

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